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Galectin Therapeutics plasma galectin 3
Plasma Galectin 3, supplied by Galectin Therapeutics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/plasma+galectin-3/lgals3/pm41871713-332-13-14
Average 86 stars, based on 1 article reviews
plasma galectin 3 - by Bioz Stars, 2026-09
86/100 stars

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Related Articles

Clinical Proteomics:

Article Title: Cardiorenal syndrome. Prognostic value of renal biomarkers. Literature review
Article Snippet: Clinical Implications of Plasma Galectin-3 in Heart Failure With Preserved Ejection Fraction: A Meta-Analysis.

Article Title: Clinical impact of circulating biomarkers in prediction of adverse cardiac events in patients with congenital heart disease. A systematic review.
Article Snippet: Global Longitudinal Strain of the Systemic Ventricle Is Correlated with Plasma Galectin-3 and Predicts Major Cardiovascular Events in Adult Patients with Congenital Heart Disease.

Article Title: Diosmin and Hesperidin Have a Protective Effect in Diabetic Neuropathy via the FGF21 and Galectin-3 Pathway
Article Snippet: Plasma Galectin-3 (ng/mL) , 5.6 ± 0.3 , 11.8 ± 1.05 ** , 8.6 ± 0.7 # , 7.3 ± 0.2 #.

Article Title: Galectin-3 in biliary atresia and other pediatric cholestatic liver diseases.
Article Snippet: Aims: Biliary atresia (BA) is characterized by intrahepatic inflammation and rapid progression of liver fibrosis.. Galectin‐3, a beta‐galactoside binding protein, is a key regulator of inflammation and fibrosis.. The aim of this study was to characterize circulating and hepatic Galectin‐3 levels in children with BA.

Article Title: Significance of Galectin-3 and N-terminal pro b-type natriuretic peptide in the prediction of atrial fibrillation after cardiac surgery
Article Snippet: The plasma Galectin-3 and NT-proBNP levels were measured one day before surgery postoperative days 1 and 7.

Article Title: Cardiorenal Syndrome in Heart Failure with Preserved Ejection Fraction: Insights into Pathophysiology and Recent Advances.
Article Snippet: Relationship of Plasma Galectin‐3 to Renal Function in Patients With Heart Failure: Effects of Clinical Status, Pathophysiology of Heart Failure, and Presence or Absence of Heart Failure.

Control:

Article Title: Cardiorenal syndrome. Prognostic value of renal biomarkers. Literature review
Article Snippet: Clinical Implications of Plasma Galectin-3 in Heart Failure With Preserved Ejection Fraction: A Meta-Analysis.

Article Title: Clinical impact of circulating biomarkers in prediction of adverse cardiac events in patients with congenital heart disease. A systematic review.
Article Snippet: Global Longitudinal Strain of the Systemic Ventricle Is Correlated with Plasma Galectin-3 and Predicts Major Cardiovascular Events in Adult Patients with Congenital Heart Disease.

Article Title: Diosmin and Hesperidin Have a Protective Effect in Diabetic Neuropathy via the FGF21 and Galectin-3 Pathway
Article Snippet: Plasma Galectin-3 (ng/mL) , 5.6 ± 0.3 , 11.8 ± 1.05 ** , 8.6 ± 0.7 # , 7.3 ± 0.2 #.

Article Title: Galectin-3 in biliary atresia and other pediatric cholestatic liver diseases.
Article Snippet: Aims: Biliary atresia (BA) is characterized by intrahepatic inflammation and rapid progression of liver fibrosis.. Galectin‐3, a beta‐galactoside binding protein, is a key regulator of inflammation and fibrosis.. The aim of this study was to characterize circulating and hepatic Galectin‐3 levels in children with BA.

Article Title: Significance of Galectin-3 and N-terminal pro b-type natriuretic peptide in the prediction of atrial fibrillation after cardiac surgery
Article Snippet: The plasma Galectin-3 and NT-proBNP levels were measured one day before surgery postoperative days 1 and 7.

Article Title: Cardiorenal Syndrome in Heart Failure with Preserved Ejection Fraction: Insights into Pathophysiology and Recent Advances.
Article Snippet: Relationship of Plasma Galectin‐3 to Renal Function in Patients With Heart Failure: Effects of Clinical Status, Pathophysiology of Heart Failure, and Presence or Absence of Heart Failure.

Saline:

Article Title: Cardiorenal syndrome. Prognostic value of renal biomarkers. Literature review
Article Snippet: Clinical Implications of Plasma Galectin-3 in Heart Failure With Preserved Ejection Fraction: A Meta-Analysis.

Article Title: Clinical impact of circulating biomarkers in prediction of adverse cardiac events in patients with congenital heart disease. A systematic review.
Article Snippet: Global Longitudinal Strain of the Systemic Ventricle Is Correlated with Plasma Galectin-3 and Predicts Major Cardiovascular Events in Adult Patients with Congenital Heart Disease.

Article Title: Diosmin and Hesperidin Have a Protective Effect in Diabetic Neuropathy via the FGF21 and Galectin-3 Pathway
Article Snippet: Plasma Galectin-3 (ng/mL) , 5.6 ± 0.3 , 11.8 ± 1.05 ** , 8.6 ± 0.7 # , 7.3 ± 0.2 #.

Article Title: Galectin-3 in biliary atresia and other pediatric cholestatic liver diseases.
Article Snippet: Aims: Biliary atresia (BA) is characterized by intrahepatic inflammation and rapid progression of liver fibrosis.. Galectin‐3, a beta‐galactoside binding protein, is a key regulator of inflammation and fibrosis.. The aim of this study was to characterize circulating and hepatic Galectin‐3 levels in children with BA.

Article Title: Significance of Galectin-3 and N-terminal pro b-type natriuretic peptide in the prediction of atrial fibrillation after cardiac surgery
Article Snippet: The plasma Galectin-3 and NT-proBNP levels were measured one day before surgery postoperative days 1 and 7.

Article Title: Cardiorenal Syndrome in Heart Failure with Preserved Ejection Fraction: Insights into Pathophysiology and Recent Advances.
Article Snippet: Relationship of Plasma Galectin‐3 to Renal Function in Patients With Heart Failure: Effects of Clinical Status, Pathophysiology of Heart Failure, and Presence or Absence of Heart Failure.

AST Assay:

Article Title: Cardiorenal syndrome. Prognostic value of renal biomarkers. Literature review
Article Snippet: Clinical Implications of Plasma Galectin-3 in Heart Failure With Preserved Ejection Fraction: A Meta-Analysis.

Article Title: Clinical impact of circulating biomarkers in prediction of adverse cardiac events in patients with congenital heart disease. A systematic review.
Article Snippet: Global Longitudinal Strain of the Systemic Ventricle Is Correlated with Plasma Galectin-3 and Predicts Major Cardiovascular Events in Adult Patients with Congenital Heart Disease.

Article Title: Diosmin and Hesperidin Have a Protective Effect in Diabetic Neuropathy via the FGF21 and Galectin-3 Pathway
Article Snippet: Plasma Galectin-3 (ng/mL) , 5.6 ± 0.3 , 11.8 ± 1.05 ** , 8.6 ± 0.7 # , 7.3 ± 0.2 #.

Article Title: Galectin-3 in biliary atresia and other pediatric cholestatic liver diseases.
Article Snippet: Aims: Biliary atresia (BA) is characterized by intrahepatic inflammation and rapid progression of liver fibrosis.. Galectin‐3, a beta‐galactoside binding protein, is a key regulator of inflammation and fibrosis.. The aim of this study was to characterize circulating and hepatic Galectin‐3 levels in children with BA.

Article Title: Significance of Galectin-3 and N-terminal pro b-type natriuretic peptide in the prediction of atrial fibrillation after cardiac surgery
Article Snippet: The plasma Galectin-3 and NT-proBNP levels were measured one day before surgery postoperative days 1 and 7.

Article Title: Cardiorenal Syndrome in Heart Failure with Preserved Ejection Fraction: Insights into Pathophysiology and Recent Advances.
Article Snippet: Relationship of Plasma Galectin‐3 to Renal Function in Patients With Heart Failure: Effects of Clinical Status, Pathophysiology of Heart Failure, and Presence or Absence of Heart Failure.

Binding Assay:

Article Title: Cardiorenal syndrome. Prognostic value of renal biomarkers. Literature review
Article Snippet: Clinical Implications of Plasma Galectin-3 in Heart Failure With Preserved Ejection Fraction: A Meta-Analysis.

Article Title: Clinical impact of circulating biomarkers in prediction of adverse cardiac events in patients with congenital heart disease. A systematic review.
Article Snippet: Global Longitudinal Strain of the Systemic Ventricle Is Correlated with Plasma Galectin-3 and Predicts Major Cardiovascular Events in Adult Patients with Congenital Heart Disease.

Article Title: Diosmin and Hesperidin Have a Protective Effect in Diabetic Neuropathy via the FGF21 and Galectin-3 Pathway
Article Snippet: Plasma Galectin-3 (ng/mL) , 5.6 ± 0.3 , 11.8 ± 1.05 ** , 8.6 ± 0.7 # , 7.3 ± 0.2 #.

Article Title: Galectin-3 in biliary atresia and other pediatric cholestatic liver diseases.
Article Snippet: Aims: Biliary atresia (BA) is characterized by intrahepatic inflammation and rapid progression of liver fibrosis.. Galectin‐3, a beta‐galactoside binding protein, is a key regulator of inflammation and fibrosis.. The aim of this study was to characterize circulating and hepatic Galectin‐3 levels in children with BA.

Article Title: Significance of Galectin-3 and N-terminal pro b-type natriuretic peptide in the prediction of atrial fibrillation after cardiac surgery
Article Snippet: The plasma Galectin-3 and NT-proBNP levels were measured one day before surgery postoperative days 1 and 7.

Article Title: Cardiorenal Syndrome in Heart Failure with Preserved Ejection Fraction: Insights into Pathophysiology and Recent Advances.
Article Snippet: Relationship of Plasma Galectin‐3 to Renal Function in Patients With Heart Failure: Effects of Clinical Status, Pathophysiology of Heart Failure, and Presence or Absence of Heart Failure.

Enzyme-linked Immunosorbent Assay:

Article Title: Cardiorenal syndrome. Prognostic value of renal biomarkers. Literature review
Article Snippet: Clinical Implications of Plasma Galectin-3 in Heart Failure With Preserved Ejection Fraction: A Meta-Analysis.

Article Title: Clinical impact of circulating biomarkers in prediction of adverse cardiac events in patients with congenital heart disease. A systematic review.
Article Snippet: Global Longitudinal Strain of the Systemic Ventricle Is Correlated with Plasma Galectin-3 and Predicts Major Cardiovascular Events in Adult Patients with Congenital Heart Disease.

Article Title: Diosmin and Hesperidin Have a Protective Effect in Diabetic Neuropathy via the FGF21 and Galectin-3 Pathway
Article Snippet: Plasma Galectin-3 (ng/mL) , 5.6 ± 0.3 , 11.8 ± 1.05 ** , 8.6 ± 0.7 # , 7.3 ± 0.2 #.

Article Title: Galectin-3 in biliary atresia and other pediatric cholestatic liver diseases.
Article Snippet: Aims: Biliary atresia (BA) is characterized by intrahepatic inflammation and rapid progression of liver fibrosis.. Galectin‐3, a beta‐galactoside binding protein, is a key regulator of inflammation and fibrosis.. The aim of this study was to characterize circulating and hepatic Galectin‐3 levels in children with BA.

Article Title: Significance of Galectin-3 and N-terminal pro b-type natriuretic peptide in the prediction of atrial fibrillation after cardiac surgery
Article Snippet: The plasma Galectin-3 and NT-proBNP levels were measured one day before surgery postoperative days 1 and 7.

Article Title: Cardiorenal Syndrome in Heart Failure with Preserved Ejection Fraction: Insights into Pathophysiology and Recent Advances.
Article Snippet: Relationship of Plasma Galectin‐3 to Renal Function in Patients With Heart Failure: Effects of Clinical Status, Pathophysiology of Heart Failure, and Presence or Absence of Heart Failure.

Cell Counting:

Article Title: Cardiorenal syndrome. Prognostic value of renal biomarkers. Literature review
Article Snippet: Clinical Implications of Plasma Galectin-3 in Heart Failure With Preserved Ejection Fraction: A Meta-Analysis.

Article Title: Clinical impact of circulating biomarkers in prediction of adverse cardiac events in patients with congenital heart disease. A systematic review.
Article Snippet: Global Longitudinal Strain of the Systemic Ventricle Is Correlated with Plasma Galectin-3 and Predicts Major Cardiovascular Events in Adult Patients with Congenital Heart Disease.

Article Title: Diosmin and Hesperidin Have a Protective Effect in Diabetic Neuropathy via the FGF21 and Galectin-3 Pathway
Article Snippet: Plasma Galectin-3 (ng/mL) , 5.6 ± 0.3 , 11.8 ± 1.05 ** , 8.6 ± 0.7 # , 7.3 ± 0.2 #.

Article Title: Galectin-3 in biliary atresia and other pediatric cholestatic liver diseases.
Article Snippet: Aims: Biliary atresia (BA) is characterized by intrahepatic inflammation and rapid progression of liver fibrosis.. Galectin‐3, a beta‐galactoside binding protein, is a key regulator of inflammation and fibrosis.. The aim of this study was to characterize circulating and hepatic Galectin‐3 levels in children with BA.

Article Title: Significance of Galectin-3 and N-terminal pro b-type natriuretic peptide in the prediction of atrial fibrillation after cardiac surgery
Article Snippet: The plasma Galectin-3 and NT-proBNP levels were measured one day before surgery postoperative days 1 and 7.

Article Title: Cardiorenal Syndrome in Heart Failure with Preserved Ejection Fraction: Insights into Pathophysiology and Recent Advances.
Article Snippet: Relationship of Plasma Galectin‐3 to Renal Function in Patients With Heart Failure: Effects of Clinical Status, Pathophysiology of Heart Failure, and Presence or Absence of Heart Failure.

Comparison:

Article Title: Cardiorenal syndrome. Prognostic value of renal biomarkers. Literature review
Article Snippet: Clinical Implications of Plasma Galectin-3 in Heart Failure With Preserved Ejection Fraction: A Meta-Analysis.

Article Title: Clinical impact of circulating biomarkers in prediction of adverse cardiac events in patients with congenital heart disease. A systematic review.
Article Snippet: Global Longitudinal Strain of the Systemic Ventricle Is Correlated with Plasma Galectin-3 and Predicts Major Cardiovascular Events in Adult Patients with Congenital Heart Disease.

Article Title: Diosmin and Hesperidin Have a Protective Effect in Diabetic Neuropathy via the FGF21 and Galectin-3 Pathway
Article Snippet: Plasma Galectin-3 (ng/mL) , 5.6 ± 0.3 , 11.8 ± 1.05 ** , 8.6 ± 0.7 # , 7.3 ± 0.2 #.

Article Title: Galectin-3 in biliary atresia and other pediatric cholestatic liver diseases.
Article Snippet: Aims: Biliary atresia (BA) is characterized by intrahepatic inflammation and rapid progression of liver fibrosis.. Galectin‐3, a beta‐galactoside binding protein, is a key regulator of inflammation and fibrosis.. The aim of this study was to characterize circulating and hepatic Galectin‐3 levels in children with BA.

Article Title: Significance of Galectin-3 and N-terminal pro b-type natriuretic peptide in the prediction of atrial fibrillation after cardiac surgery
Article Snippet: The plasma Galectin-3 and NT-proBNP levels were measured one day before surgery postoperative days 1 and 7.

Article Title: Cardiorenal Syndrome in Heart Failure with Preserved Ejection Fraction: Insights into Pathophysiology and Recent Advances.
Article Snippet: Relationship of Plasma Galectin‐3 to Renal Function in Patients With Heart Failure: Effects of Clinical Status, Pathophysiology of Heart Failure, and Presence or Absence of Heart Failure.



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Galectin Therapeutics plasma galectin 3
Plasma Galectin 3, supplied by Galectin Therapeutics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/plasma+galectin-3/lgals3/pm41871713-332-13-14
Average 86 stars, based on 1 article reviews
plasma galectin 3 - by Bioz Stars, 2026-09
86/100 stars
  Buy from Supplier

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Galectin Therapeutics plasma galectin 3 levels
An overview of cytokine factors related signaling pathways that are involved in TBI. I. Injured neurons release damage-associated molecular patterns (DAMPs) and HMGB1, which bind to TLR4. This activates microglia to produce more inflammatory factors and <t>Galectin-3.</t> At the same time, it initiates a cascade reaction with MyD88, promoting the entry of NF-κB into the nucleus to bind to the promoter and up-regulate the expression of NLPR3 and GMF. This accelerates the release of IL-1β and IL-18. Galectin-3 can also initiate an inflammatory response by binding to the TLR4 receptor. II. The binding of ligands (growth factors and cytokines) to specific receptors triggers a cascade reaction of MAPKs. These are activated by phosphorylation and ultimately induce microglia activation, oxidative stress, and blood-brain barrier damage. III. TGFβ1 binds to the receptor and initiates Smads protein phosphorylation. This inhibits microglia activation and protects the nerves, preventing myelin shedding. IV. After TBI, epidermal growth factor and insulin growth factor bind to tyrosine kinase receptors, initiating a cascade reaction that activates Akt. Akt participates in apoptosis by regulating the phosphorylation of the pro-apoptotic mediator GSK-3β.
Plasma Galectin 3 Levels, supplied by Galectin Therapeutics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/plasma+galectin-3/lgals3/pmc12932479-269-1-2
Average 86 stars, based on 1 article reviews
plasma galectin 3 levels - by Bioz Stars, 2026-09
86/100 stars
  Buy from Supplier

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Galectin Therapeutics high plasma galectin 3 levels
An overview of cytokine factors related signaling pathways that are involved in TBI. I. Injured neurons release damage-associated molecular patterns (DAMPs) and HMGB1, which bind to TLR4. This activates microglia to produce more inflammatory factors and <t>Galectin-3.</t> At the same time, it initiates a cascade reaction with MyD88, promoting the entry of NF-κB into the nucleus to bind to the promoter and up-regulate the expression of NLPR3 and GMF. This accelerates the release of IL-1β and IL-18. Galectin-3 can also initiate an inflammatory response by binding to the TLR4 receptor. II. The binding of ligands (growth factors and cytokines) to specific receptors triggers a cascade reaction of MAPKs. These are activated by phosphorylation and ultimately induce microglia activation, oxidative stress, and blood-brain barrier damage. III. TGFβ1 binds to the receptor and initiates Smads protein phosphorylation. This inhibits microglia activation and protects the nerves, preventing myelin shedding. IV. After TBI, epidermal growth factor and insulin growth factor bind to tyrosine kinase receptors, initiating a cascade reaction that activates Akt. Akt participates in apoptosis by regulating the phosphorylation of the pro-apoptotic mediator GSK-3β.
High Plasma Galectin 3 Levels, supplied by Galectin Therapeutics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/plasma+galectin-3/lgals3/pm40341412-126-0-2
Average 86 stars, based on 1 article reviews
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An overview of cytokine factors related signaling pathways that are involved in TBI. I. Injured neurons release damage-associated molecular patterns (DAMPs) and HMGB1, which bind to TLR4. This activates microglia to produce more inflammatory factors and Galectin-3. At the same time, it initiates a cascade reaction with MyD88, promoting the entry of NF-κB into the nucleus to bind to the promoter and up-regulate the expression of NLPR3 and GMF. This accelerates the release of IL-1β and IL-18. Galectin-3 can also initiate an inflammatory response by binding to the TLR4 receptor. II. The binding of ligands (growth factors and cytokines) to specific receptors triggers a cascade reaction of MAPKs. These are activated by phosphorylation and ultimately induce microglia activation, oxidative stress, and blood-brain barrier damage. III. TGFβ1 binds to the receptor and initiates Smads protein phosphorylation. This inhibits microglia activation and protects the nerves, preventing myelin shedding. IV. After TBI, epidermal growth factor and insulin growth factor bind to tyrosine kinase receptors, initiating a cascade reaction that activates Akt. Akt participates in apoptosis by regulating the phosphorylation of the pro-apoptotic mediator GSK-3β.

Journal: Frontiers in Immunology

Article Title: Cytokines and related signaling pathways in traumatic brain injury

doi: 10.3389/fimmu.2026.1738589

Figure Lengend Snippet: An overview of cytokine factors related signaling pathways that are involved in TBI. I. Injured neurons release damage-associated molecular patterns (DAMPs) and HMGB1, which bind to TLR4. This activates microglia to produce more inflammatory factors and Galectin-3. At the same time, it initiates a cascade reaction with MyD88, promoting the entry of NF-κB into the nucleus to bind to the promoter and up-regulate the expression of NLPR3 and GMF. This accelerates the release of IL-1β and IL-18. Galectin-3 can also initiate an inflammatory response by binding to the TLR4 receptor. II. The binding of ligands (growth factors and cytokines) to specific receptors triggers a cascade reaction of MAPKs. These are activated by phosphorylation and ultimately induce microglia activation, oxidative stress, and blood-brain barrier damage. III. TGFβ1 binds to the receptor and initiates Smads protein phosphorylation. This inhibits microglia activation and protects the nerves, preventing myelin shedding. IV. After TBI, epidermal growth factor and insulin growth factor bind to tyrosine kinase receptors, initiating a cascade reaction that activates Akt. Akt participates in apoptosis by regulating the phosphorylation of the pro-apoptotic mediator GSK-3β.

Article Snippet: Clinically, plasma Galectin-3 levels correlate positively with Glasgow Coma Scale scores (r = 0.72, p < 0.001), underscoring its potential as a prognostic biomarker for TBI severity ( ).

Techniques: Protein-Protein interactions, Expressing, Binding Assay, Phospho-proteomics, Activation Assay